Axel Le Cesne Selected Research

Aftercare (After-Treatment)

12/2022	Quality of Sarcoma Care: Longitudinal Real-Time Assessment and Evidence Analytics of Quality Indicators.
12/2022	Ripretinib Versus Sunitinib in Patients With Advanced Gastrointestinal Stromal Tumor After Treatment With Imatinib (INTRIGUE): A Randomized, Open-Label, Phase III Trial.
6/2015	Reply to Letter: A Role for Adjuvant RFA in Managing Hepatic Metastases From Gastrointestinal Stromal Tumors (GIST) After Treatment With Targeted Systemic Therapy Using Kinase Inhibitors.
2/2014	A role for adjuvant RFA in managing hepatic metastases from gastrointestinal stromal tumors (GIST) after treatment with targeted systemic therapy using kinase inhibitors.
4/2005	Role of computed tomography in the follow-up of hepatic and peritoneal metastases of GIST under imatinib mesylate treatment: a prospective study of 54 patients.

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Axel Le Cesne Research Topics

Disease

100	Sarcoma (Soft Tissue Sarcoma) 02/2024 - 08/2005
79	Neoplasms (Cancer) 03/2024 - 01/2003
34	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2024 - 08/2004
19	Leiomyosarcoma 09/2022 - 11/2005
16	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2004
15	Disease Progression 01/2024 - 06/2012
12	Liposarcoma 11/2023 - 07/2007
11	Fatigue 09/2022 - 09/2006
9	Aggressive Fibromatosis (Desmoid) 01/2021 - 06/2003
9	Neutropenia 01/2019 - 07/2007
8	Synovial Sarcoma (Synovioma) 03/2024 - 04/2008
8	Hemangiosarcoma (Angiosarcoma) 05/2023 - 01/2012
7	Nausea 09/2022 - 09/2006
5	Myxoid Liposarcoma 03/2024 - 07/2007
5	Osteosarcoma (Osteogenic Sarcoma) 01/2022 - 08/2012
5	Hypertension (High Blood Pressure) 01/2020 - 07/2009
4	Thrombocytopenia (Thrombopenia) 12/2023 - 10/2008
3	Breast Neoplasms (Breast Cancer) 01/2024 - 07/2009
3	Pain (Aches) 12/2023 - 01/2017
3	Fibroma (Fibromatosis) 01/2021 - 12/2009
3	Genetic Translocation (Chromosomal Translocation) 01/2019 - 07/2007
3	Febrile Neutropenia 04/2015 - 07/2007
2	Ewing Sarcoma (Sarcoma, Ewing) 12/2023 - 08/2012
2	Vomiting 09/2022 - 06/2012
2	Lymphopenia (Lymphocytopenia) 01/2020 - 07/2009
2	Cardiotoxicity 01/2020 - 04/2007
2	Alveolar Soft Part Sarcoma 01/2019 - 01/2018
2	Anorexia 01/2018 - 02/2013
2	Desmoplastic Small Round Cell Tumor 01/2017 - 04/2015
2	Chordoma 01/2017 - 01/2009
2	Epithelioid Hemangioendothelioma 09/2014 - 07/2013
2	Exanthema (Rash) 07/2013 - 09/2006
2	Alopecia (Baldness) 06/2013 - 03/2012
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 02/2024
1	Asthenia 12/2023
1	Constipation 10/2023
1	Melanoma (Melanoma, Malignant) 01/2023
1	Thyroid Neoplasms (Thyroid Cancer) 01/2023
1	Solitary Fibrous Tumors 09/2022

Drug/Important Bio-Agent (IBA)

42	Imatinib Mesylate (Gleevec)FDA Link 01/2024 - 01/2003
29	TrabectedinIBA 02/2024 - 07/2007
19	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 08/2006
15	Ifosfamide FDA LinkGeneric 03/2024 - 08/2006
12	Tyrosine Kinase InhibitorsIBA 12/2022 - 02/2009
11	Phosphotransferases (Kinase)IBA 01/2021 - 07/2005
8	AnthracyclinesIBA 03/2024 - 09/2009
8	Sunitinib (Sutent)FDA Link 01/2024 - 04/2010
7	regorafenibIBA 12/2023 - 01/2013
7	pazopanib FDA Link 01/2020 - 07/2009
6	Biomarkers (Surrogate Marker)IBA 01/2024 - 06/2012
5	Proteins (Proteins, Gene)FDA Link 12/2019 - 11/2005
5	DNA (Deoxyribonucleic Acid)IBA 12/2019 - 01/2007
5	Alanine Transaminase (SGPT)IBA 05/2015 - 10/2008
5	Sorafenib (BAY 43-9006)FDA Link 11/2014 - 04/2010
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 02/2013 - 05/2007
3	ripretinibIBA 01/2024 - 12/2022
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 09/2014
3	Etoposide (VP 16)FDA LinkGeneric 01/2021 - 02/2012
3	Gemcitabine FDA Link 01/2020 - 08/2006
3	Dacarbazine (DIC)FDA LinkGeneric 01/2020 - 04/2016
3	Docetaxel (Taxotere)FDA Link 01/2019 - 03/2004
3	Messenger RNA (mRNA)IBA 01/2019 - 08/2011
3	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2017 - 08/2004
3	Cytotoxins (Cytolysins)IBA 01/2012 - 08/2006
2	Trinitrotoluene (TNT)IBA 08/2023 - 04/2017
2	Vinorelbine (Navelbine)FDA LinkGeneric 01/2021 - 12/2020
2	Transaminases (Aminotransferases)IBA 01/2020 - 06/2012
2	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 02/2012
2	RNA (Ribonucleic Acid)IBA 12/2019 - 01/2008
2	Oncogene Proteins (Oncogene Protein)IBA 01/2019 - 11/2012
2	Bevacizumab (Avastin)FDA Link 10/2018 - 09/2015
2	Paclitaxel (Taxol)FDA LinkGeneric 10/2018 - 09/2015
2	nilotinib FDA Link 01/2018 - 05/2015
2	eribulin FDA Link 04/2016 - 10/2011
2	Codon (Codons)IBA 10/2013 - 07/2004
2	ridaforolimusIBA 07/2013 - 08/2012
2	EnzymesIBA 02/2013 - 07/2009
2	Angiogenesis InhibitorsIBA 05/2012 - 07/2009
2	Melphalan (Alkeran)FDA LinkGeneric 02/2012 - 12/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2012 - 12/2009
2	Gefitinib (Iressa)FDA Link 04/2008 - 02/2005
1	HLA-A Antigens (HLA-A)IBA 03/2024
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 03/2024
1	PM 01183IBA 02/2024
1	Immunoconjugates (Immunoconjugate)IBA 01/2024
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2023
1	pembrolizumabIBA 01/2023
1	Shelterin ComplexIBA 01/2023
1	Immune Checkpoint InhibitorsIBA 01/2023
1	selinexorIBA 01/2022
1	Dihydrotachysterol (AT 10)IBA 01/2022

Therapy/Procedure

45	Therapeutics 03/2024 - 11/2004
43	Drug Therapy (Chemotherapy) 03/2024 - 01/2003
11	Radiotherapy 01/2022 - 02/2006
6	Adjuvant Chemotherapy 01/2022 - 11/2006
5	Aftercare (After-Treatment) 12/2022 - 04/2005
4	Neoadjuvant Therapy 09/2021 - 11/2006
4	Combination Drug Therapy (Combination Chemotherapy) 01/2019 - 10/2011
3	Immunotherapy 01/2023 - 05/2007
2	Brachytherapy 01/2022 - 02/2006